TUFT1

Across TCGA patient cohorts, TUFT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,825 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TUFT1-associated proteins across cancer lineages are TUFT1_S378, JUP, and BROX. Each is linked with TUFT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both TUFT1-to-partner and partner-to-TUFT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TUFT1 versus TUFT1_S378 in LSCC, with a Pearson correlation of 0.81.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TUFT1→partner) and Y-score (partner→TUFT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TUFT1_S378 →	+1.329	+1.463	<.001	<.001	3	6
LSCC	JUP →	+0.637	+0.900	<.001	<.001	3	6
BRCA	BROX →	+0.406	+0.725	<.001	<.001	3	6
PDAC	PMVK →	+0.526	+0.716	<.001	<.001	3	6
LSCC	ARHGEF6_S225 →	-0.593	-0.836	<.001	<.001	3	6
HNSC	PTPRC →	-0.449	-0.593	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,825 associations by consensus.

TUFT1 vs TUFT1_S378 — LSCC

Explore this scatter interactively →