TUFT1

Across TCGA cell cohorts, TUFT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,446 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TUFT1-associated GO terms across cancer lineages are Positive regulation of purine nucleotide biosynthetic process, Positive regulation of ATP biosynthetic process, and Positive regulation of nucleotide biosynthetic process. Each is linked with TUFT1 in more than 13 cancer types. Because this analysis shows association rather than direction, both TUFT1-to-partner and partner-to-TUFT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of purine nucleotide biosynthetic process grouped by TUFT1-low versus TUFT1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUFT1→partner) and Y-score (partner→TUFT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Positive regulation of purine nucleotide biosynthetic process →	+0.158	+1.107	<.001	<.001	3	14
LARGE_INTESTINE	Positive regulation of ATP biosynthetic process →	+0.157	+1.107	<.001	<.001	3	14
LARGE_INTESTINE	Positive regulation of nucleotide biosynthetic process →	+0.158	+1.107	<.001	<.001	3	14
OVARY	Positive regulation of exosomal secretion →	+0.105	+1.390	<.001	<.001	3	13
URINARY_TRACT	Membrane fission →	+0.076	+1.767	<.001	.002	3	12
STOMACH	Establishment of protein localization to membrane →	+0.083	+2.076	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,446 associations by consensus.

Positive regulation of purine nucleotide biosynthetic process by TUFT1 expression — LARGE_INTESTINE

Explore this box plot interactively →