TUFMP1

Across TCGA pan-cancer cohorts, TUFMP1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of TUFMP1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where TUFMP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TUFMP1 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

COAD, LUAD, and BRCA are the cancer types where TUFMP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TUFMP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+0.811	<.001	7	view →
LUAD	All	II,III,IV	+0.137	.013	5	view →
BRCA	All	All	+0.089	<.001	4	view →
BLCA	Male	III,IV	+0.110	.025	3	view →
LUSC	All	All	+0.414	.018	2	view →
STAD	All	II,III,IV	+0.207	.036	2	view →
LIHC	All	All	+0.183	.009	2	view →
CHOL	All	II,III,IV	+0.075	.004	2	view →
PRAD	All	All	+0.044	.016	2	view →
KIRC	Male	IV	−0.073	.048	1	view →
HNSC	Male	All	+0.046	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

TUFMP1–COAD

Open the COAD breakdown →