TUFM

Across TCGA pan-cancer cohorts, TUFM mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TUFM data layer compared with 26 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher TUFM mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated TUFM expression acts as an unfavorable survival marker, although some lineages such as GBM and COAD show a favorable association.

GBM, COAD, and LSCC are the cancer types where TUFM mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Median	All	0.455	0.290	.010	20	view →
COAD	DFS	Tertile	II,III,IV	1.000	0.878	.046	12	view →
LSCC	OS	Tertile	II,III,IV	0.948	0.622	.012	9	view →
LUAD	OS	Quartile	All	0.977	0.807	.027	5	view →
CCRCC	DFS	Tertile	II,III,IV	0.437	0.736	.042	4	view →
HNSC	DFS	Quartile	II,III,IV	0.534	0.804	.013	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TUFM–GBM (OS)

Open the GBM breakdown →