TUFM

Across TCGA cell cohorts, TUFM RNA expression is significantly associated with the go_rna of many other GO terms, with 4,098 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TUFM-associated GO terms across cancer lineages are Ribosomal large subunit assembly, Mitochondrial ribosome assembly, and Ribosome assembly. Each is linked with TUFM in more than 17 cancer types. Because this analysis shows association rather than direction, both TUFM-to-partner and partner-to-TUFM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal large subunit assembly grouped by TUFM-low versus TUFM-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUFM→partner) and Y-score (partner→TUFM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Ribosomal large subunit assembly →	+0.107	+0.636	<.001	<.001	3	18
BLOOD_Myeloma	Mitochondrial ribosome assembly →	+0.095	+0.755	.001	.002	3	17
BLOOD_Myeloma	Ribosome assembly →	+0.103	+0.709	<.001	.004	3	16
BONE	Pseudouridine synthesis →	+0.119	+0.603	<.001	<.001	3	15
LUNG_SCLC	Amino acid activation →	+0.093	+0.711	<.001	<.001	3	15
LUNG_SCLC	tRNA aminoacylation →	+0.093	+0.711	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,098 associations by consensus.

Ribosomal large subunit assembly by TUFM expression — BLOOD_Lymphoma

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