TUBGCP6

Across TCGA patient cohorts, TUBGCP6 mutation is significantly associated with the total protein of many other genes, with 66 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBGCP6-associated genes across cancer lineages are TFRC, c-Kit, and C-Raf. Each is linked with TUBGCP6 in more than 3 cancer types. Because this analysis shows association rather than direction, both TUBGCP6-to-partner and partner-to-TUBGCP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by TUBGCP6-low versus TUBGCP6-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBGCP6→partner) and Y-score (partner→TUBGCP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TFRC →	+0.616	+3.033	.005	.017	3	4
STAD	c-Kit →	-0.305	-3.321	.014	.008	3	3
STAD	C-Raf →	+0.159	+3.459	.011	.004	3	3
UCEC	ATM →	-0.423	-2.308	<.001	<.001	3	3
UCEC	Cyclin-B1 →	+0.429	+1.925	.006	.004	3	3
STAD	SF2 →	+0.416	+3.169	.002	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 66 associations by consensus.

TFRC by TUBGCP6 expression — COAD

Explore this box plot interactively →