TUBGCP6

Across TCGA cell cohorts, TUBGCP6 mutation is significantly associated with the RNA expression of many other genes, with 847 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TUBGCP6-associated genes across cancer lineages are SSB, DPPA3, and DESI1. Each is linked with TUBGCP6 in more than 2 cancer types. Because this analysis shows association rather than direction, both TUBGCP6-to-partner and partner-to-TUBGCP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SSB grouped by TUBGCP6-low versus TUBGCP6-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBGCP6→partner) and Y-score (partner→TUBGCP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	SSB →	+0.541	+3.078	.005	.007	3	2
BLOOD_Lymphoma	DPPA3 →	+0.007	+3.662	<.001	.009	3	2
LARGE_INTESTINE	DESI1 →	+0.514	+2.584	<.001	.001	3	2
LARGE_INTESTINE	DDHD1 →	+0.755	+3.043	<.001	<.001	3	2
LARGE_INTESTINE	TRIM37 →	+0.475	+1.850	.008	.006	3	2
LARGE_INTESTINE	USP46 →	+0.527	+1.936	.006	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 847 associations by consensus.

SSB by TUBGCP6 expression — BREAST

Explore this box plot interactively →