TUBGCP4

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, TUBGCP4 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TUBGCP4 data layer compared with 26 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher TUBGCP4 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TUBGCP4 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, LUAD, and LSCC are the cancer types where TUBGCP4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCDFSTertileAll0.8870.359.00320view →
LUADDFSTertileIII,IV0.8900.343.0116view →
LSCCDFSMedianAll0.9020.469.0105view →
PDACOSTertileIV0.9340.425.0243view →
GBMOSMedianAll0.9050.805.0282view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TUBGCP4–CCRCC (DFS)

Kaplan–Meier survival curve for TUBGCP4 mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration