TUBGCP4

Across TCGA cell cohorts, TUBGCP4 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TUBGCP4-associated genes across cancer lineages are GML, TEX55, and MT1B. Each is linked with TUBGCP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBGCP4-to-partner and partner-to-TUBGCP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GML grouped by TUBGCP4-low versus TUBGCP4-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBGCP4→partner) and Y-score (partner→TUBGCP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	GML →	+0.034	+4.273	<.001	.006	3	1
SKIN	TEX55 →	+0.071	+4.467	<.001	.004	3	1
SKIN	MT1B →	+0.095	+4.415	<.001	.007	3	1
SKIN	OR52E2 →	+0.056	+4.930	<.001	.001	3	1
SKIN	CT47A7 →	+0.010	+5.022	<.001	.002	3	1
BREAST	OR10K2 →	+0.063	+5.781	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

GML by TUBGCP4 expression — SKIN

Explore this box plot interactively →