TUBGCP3

Across TCGA pan-cancer cohorts, TUBGCP3 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TUBGCP3 data layer compared with 26 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TUBGCP3 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TUBGCP3 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

HNSC, CCRCC, and LUAD are the cancer types where TUBGCP3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	III,IV	0.677	0.892	.003	42	view →
CCRCC	OS	Quartile	III,IV	0.929	0.509	.006	27	view →
LUAD	DFS	Tertile	II,III,IV	0.943	0.751	.010	6	view →
PDAC	DFS	Quartile	All	0.626	0.805	.031	5	view →
LSCC	OS	Median	All	0.800	1.000	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TUBGCP3–HNSC (DFS)

Open the HNSC breakdown →