TUBGCP2

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, TUBGCP2 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TUBGCP2 data layer compared with 26 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher TUBGCP2 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated TUBGCP2 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, PDAC, and HNSC are the cancer types where TUBGCP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCOSTertileIII,IV0.8870.455<.00157view →
PDACDFSMedianIV0.2140.785.00618view →
HNSCDFSTertileIII,IV0.6820.924.01314view →
LUADDFSQuartileII,III,IV1.0000.797.0372view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TUBGCP2–CCRCC (OS)

Kaplan–Meier survival curve for TUBGCP2 mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration