TUBGCP2

Across TCGA cell cohorts, TUBGCP2 mutation is significantly associated with the RNA expression of many other genes, with 358 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TUBGCP2-associated genes across cancer lineages are CCL13, CCL18, and TCP11X1. Each is linked with TUBGCP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBGCP2-to-partner and partner-to-TUBGCP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL13 grouped by TUBGCP2-low versus TUBGCP2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBGCP2→partner) and Y-score (partner→TUBGCP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CCL13 →	+0.034	+4.662	<.001	.005	3	2
LUNG_NSCLC_LUAD	CCL18 →	+0.026	+4.212	.005	.007	3	2
CNS	TCP11X1 →	+0.020	+4.472	<.001	.004	3	2
SKIN	RBMY1F →	+0.052	+4.437	<.001	.004	3	2
SKIN	OR13C3 →	+0.018	+4.437	<.001	.004	3	2
URINARY_TRACT	PCDH11Y →	+0.016	+5.087	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 358 associations by consensus.

CCL13 by TUBGCP2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →