TUBG1

Across TCGA pan-cancer cohorts, TUBG1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TUBG1 data layer compared with 23 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher TUBG1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TUBG1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, HNSC, and LSCC are the cancer types where TUBG1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	II,III,IV	1.000	0.693	.005	24	view →
HNSC	OS	Median	All	0.788	0.914	.009	23	view →
LSCC	DFS	Quartile	III,IV	0.277	0.926	.001	19	view →
LUAD	DFS	Tertile	III,IV	0.995	0.475	.003	6	view →
PDAC	OS	Tertile	IV	0.231	0.916	.024	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TUBG1–CCRCC (DFS)

Open the CCRCC breakdown →