TUBG1

Across TCGA cell cohorts, TUBG1 mutation is significantly associated with the mutation status of many other genes, with 3,357 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TUBG1-associated genes across cancer lineages are FGD3, CNMD, and HPD. Each is linked with TUBG1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TUBG1-to-partner and partner-to-TUBG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FGD3 grouped by TUBG1-low versus TUBG1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBG1→partner) and Y-score (partner→TUBG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FGD3 →	+4.700	+5.050	<.001	<.001	1	3
BLOOD_Leukemia	CNMD →	+4.285	+4.285	.001	.001	1	3
LARGE_INTESTINE	HPD →	+4.087	+5.044	.001	.001	1	3
BLOOD_Leukemia	ANGPTL4 →	+5.285	+4.321	.005	.005	1	3
LARGE_INTESTINE	DOLK →	+5.087	+4.523	.006	.006	1	3
BLOOD_Leukemia	RNF182 →	+4.870	+4.560	<.001	<.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,357 associations by consensus.

FGD3 by TUBG1 expression — BLOOD_Leukemia

Explore this box plot interactively →