TUBE1

Across TCGA pan-cancer cohorts, TUBE1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TUBE1 data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TUBE1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TUBE1 expression acts as an unfavorable survival marker.

HNSC, LUAD, and UCEC are the cancer types where TUBE1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	All	0.475	0.829	.007	13	view →
LUAD	OS	Quartile	II,III,IV	0.307	0.801	.013	8	view →
UCEC	OS	Median	III,IV	0.462	0.884	.009	8	view →
PDAC	DFS	Median	All	0.160	0.623	.006	6	view →
GBM	OS	Quartile	All	0.821	1.000	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TUBE1–HNSC (DFS)

Open the HNSC breakdown →