TUBE1

Across TCGA cell cohorts, TUBE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,824 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TUBE1-associated GO terms across cancer lineages are Formate biosynthetic process, Negative regulation of hematopoietic stem cell differentiation, and ATF6-mediated unfolded protein response. Each is linked with TUBE1 in more than 12 cancer types. Because this analysis shows association rather than direction, both TUBE1-to-partner and partner-to-TUBE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Formate biosynthetic process grouped by TUBE1-low versus TUBE1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBE1→partner) and Y-score (partner→TUBE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Formate biosynthetic process →	+0.167	+1.290	<.001	<.001	3	13
LARGE_INTESTINE	Negative regulation of hematopoietic stem cell differentiation →	+0.144	+1.715	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	ATF6-mediated unfolded protein response →	+0.143	+0.850	.001	.006	3	12
LARGE_INTESTINE	Serine family amino acid biosynthetic process →	+0.158	+1.051	<.001	.009	2	12
BLOOD_Lymphoma	Protein localization to non-motile cilium →	+0.053	+1.201	.001	<.001	3	11
LUNG_NSCLC_LUSC	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process →	+0.106	+0.818	.008	.008	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,824 associations by consensus.

Formate biosynthetic process by TUBE1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →