TUBD1

Across TCGA patient cohorts, TUBD1 mutation is significantly associated with the RNA expression of many other genes, with 517 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBD1-associated genes across cancer lineages are SNORD115-9, RNA5SP463, and RNU6-440P. Each is linked with TUBD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBD1-to-partner and partner-to-TUBD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD115-9 grouped by TUBD1-low versus TUBD1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBD1→partner) and Y-score (partner→TUBD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SNORD115-9 →	+0.134	+7.057	<.001	.009	3	2
UCEC	RNA5SP463 →	+0.496	+2.480	<.001	.002	3	2
SKCM	RNU6-440P →	+0.355	+8.228	<.001	<.001	3	2
LUAD	IGKV2-19 →	+0.141	+5.481	.006	.005	3	2
SKCM	RNU1-117P →	+0.282	+6.993	<.001	<.001	3	2
CESC	MATR3P1 →	+0.219	+5.418	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 517 associations by consensus.

SNORD115-9 by TUBD1 expression — BRCA

Explore this box plot interactively →