TUBD1

Across TCGA patient cohorts, TUBD1 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBD1-associated genes across cancer lineages are JNK_pT183_Y185, Ku80, and PKC-delta_pS664. Each is linked with TUBD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBD1-to-partner and partner-to-TUBD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK_pT183_Y185 grouped by TUBD1-low versus TUBD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBD1→partner) and Y-score (partner→TUBD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.200	-3.308	.023	.010	3	1
UCEC	Ku80 →	+0.303	+3.335	.014	.005	3	1
UCEC	PKC-delta_pS664 →	-0.160	-2.999	.011	.035	3	1
UCEC	PR →	-0.258	-2.999	.049	.035	3	1
UCEC	Rad50 →	-0.283	-3.321	.026	.010	3	1
UCEC	Annexin-1 →	+0.709	+2.827	.010	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

JNK_pT183_Y185 by TUBD1 expression — UCEC

Explore this box plot interactively →