Across TCGA pan-cancer cohorts, TUBBP9 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of TUBBP9’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where TUBBP9 RNA is repressed in tumor relative to normal tissue. In most cancer types TUBBP9 is over-expressed in tumor, although a few such as BRCA and THCA show the opposite, repressed pattern.
BRCA, THCA, and LUAD are the cancer types where TUBBP9 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TUBBP9 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.