TUBBP8

Across TCGA patient cohorts, TUBBP8 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,645 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TUBBP8-associated GO terms across cancer lineages are Mitotic DNA integrity checkpoint signaling, Establishment of protein localization to membrane, and Transport along microtubule. Each is linked with TUBBP8 in more than 15 cancer types. Because this analysis shows association rather than direction, both TUBBP8-to-partner and partner-to-TUBBP8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic DNA integrity checkpoint signaling grouped by TUBBP8-low versus TUBBP8-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBBP8→partner) and Y-score (partner→TUBBP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitotic DNA integrity checkpoint signaling →	+0.064	+0.105	<.001	<.001	3	16
ESCA	Establishment of protein localization to membrane →	+0.060	+0.161	<.001	.001	3	15
STAD	Transport along microtubule →	+0.054	+0.118	<.001	<.001	3	15
STAD	DNA strand elongation →	+0.064	+0.095	<.001	<.001	3	15
STAD	Cytoskeleton-dependent intracellular transport →	+0.054	+0.119	<.001	<.001	3	15
STAD	Protein-containing complex localization →	+0.048	+0.101	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,645 associations by consensus.

Mitotic DNA integrity checkpoint signaling by TUBBP8 expression — STAD

Explore this box plot interactively →