TUBBP6

Across TCGA pan-cancer cohorts, TUBBP6 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TUBBP6 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher TUBBP6 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TUBBP6 expression acts as an unfavorable survival marker.

OV, LUSC, and UCEC are the cancer types where TUBBP6 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	II,III,IV	0.022	0.844	<.001	48	view →
LUSC	OS	Median	III,IV	0.283	0.693	.012	15	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

TUBBP6–OV (OS)

Open the OV breakdown →