TUBBP6

Across TCGA patient cohorts, TUBBP6 mutation is significantly associated with the RNA expression of many other genes, with 402 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBBP6-associated genes across cancer lineages are MIR8076, RNA5SP66, and CSGALNACT2P2. Each is linked with TUBBP6 in more than 2 cancer types. Because this analysis shows association rather than direction, both TUBBP6-to-partner and partner-to-TUBBP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8076 grouped by TUBBP6-low versus TUBBP6-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBBP6→partner) and Y-score (partner→TUBBP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MIR8076 →	+0.422	+7.495	<.001	<.001	3	3
SKCM	RNA5SP66 →	+0.090	+5.357	<.001	<.001	3	2
UCEC	CSGALNACT2P2 →	+0.107	+3.069	.004	.009	3	2
CESC	MTND4LP20 →	+0.100	+5.579	<.001	.001	3	2
LIHC	RN7SL190P →	+0.148	+5.758	<.001	.003	3	2
CESC	MIR3925 →	+0.250	+4.559	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 402 associations by consensus.

MIR8076 by TUBBP6 expression — LIHC

Explore this box plot interactively →