TUBBP6

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TUBBP6 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBBP6-associated genes across cancer lineages are Preadipocytes, Mast cells, and Adipocytes. Each is linked with TUBBP6 in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBBP6-to-partner and partner-to-TUBBP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Preadipocytes grouped by TUBBP6-low versus TUBBP6-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBBP6→partner) and Y-score (partner→TUBBP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCPreadipocytes →+0.053+3.760<.001.00731
LUADMast cells →+0.009+1.901.027.01431
UCECAdipocytes →+0.023+3.729.014.00231
UCECEndothelial cells →-0.042-3.279.034.01111
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Preadipocytes by TUBBP6 expression — CESC

Box plot of Preadipocytes in TUBBP6-low vs TUBBP6-high samples in CESC.

Explore this box plot interactively →

Exploration