TUBBP3

Across TCGA pan-cancer cohorts, TUBBP3 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TUBBP3’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where TUBBP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TUBBP3 is over-expressed in tumor.

BRCA and LUSC are the cancer types where TUBBP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TUBBP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	+0.079	.006	4	view →
LUSC	Male	All	+0.018	.027	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

TUBBP3–BRCA

Open the BRCA breakdown →