TUBBP11

Across TCGA patient cohorts, TUBBP11 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,290 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TUBBP11-associated GO terms across cancer lineages are Negative regulation of secretion, Peptide transport, and Regulation of protein localization to chromosome, telomeric region. Each is linked with TUBBP11 in more than 7 cancer types. Because this analysis shows association rather than direction, both TUBBP11-to-partner and partner-to-TUBBP11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of secretion grouped by TUBBP11-low versus TUBBP11-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBBP11→partner) and Y-score (partner→TUBBP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of secretion →	+0.057	+0.219	<.001	<.001	3	8
STAD	Peptide transport →	+0.054	+0.241	<.001	<.001	3	8
STAD	Regulation of protein localization to chromosome, telomeric region →	+0.114	+0.255	<.001	<.001	3	8
STAD	Regulation of protein secretion →	+0.065	+0.296	<.001	<.001	3	8
STAD	Vacuolar acidification →	+0.081	+0.265	<.001	<.001	3	8
STAD	ATP biosynthetic process →	+0.112	+0.267	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,290 associations by consensus.

Negative regulation of secretion by TUBBP11 expression — STAD

Explore this box plot interactively →