TUBB8P7

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, TUBB8P7 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TUBB8P7 data layer compared with 21 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher TUBB8P7 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TUBB8P7 expression acts as an unfavorable survival marker.

BRCA, HNSC, and LGG are the cancer types where TUBB8P7 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BRCAOSMedianIII,IV0.0270.907<.00116view →
HNSCOSMedianAll0.1740.710.01215view →
LGGOSMedianAll0.1910.830<.00112view →
UCECOSMedianIV0.2310.592.0366view →
SKCMDFSMedianII,III,IV0.1360.708.0183view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TUBB8P7–BRCA (OS)

Kaplan–Meier survival curve for TUBB8P7 mutant vs wild-type samples in BRCA.

Open the BRCA breakdown →

Exploration