TUBB8P7

Across TCGA patient cohorts, TUBB8P7 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBB8P7-associated genes across cancer lineages are Cyclin-B1, ACC_pS79, and ACC1. Each is linked with TUBB8P7 in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBB8P7-to-partner and partner-to-TUBB8P7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by TUBB8P7-low versus TUBB8P7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB8P7→partner) and Y-score (partner→TUBB8P7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.482	+2.807	.049	.003	3	2
UCEC	ACC_pS79 →	+0.395	+2.331	.009	.019	3	1
UCEC	ACC1 →	+0.357	+2.115	.024	.019	3	1
UCEC	IGFBP2 →	-0.721	-2.115	.011	.019	3	1
UCEC	Ku80 →	+0.234	+1.598	.023	.044	3	1
UCEC	p62 Lck ligand →	+0.371	+3.469	.009	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Cyclin-B1 by TUBB8P7 expression — UCEC

Explore this box plot interactively →