TUBB8P5

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TUBB8P5 RNA expression is significantly associated with the mutation status of many other genes, with 1,144 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBB8P5-associated genes across cancer lineages are SCN5A, PLK4, and SVEP1. Each is linked with TUBB8P5 in more than 2 cancer types. Because this analysis shows association rather than direction, both TUBB8P5-to-partner and partner-to-TUBB8P5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCN5A grouped by TUBB8P5-low versus TUBB8P5-high in HNSC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB8P5→partner) and Y-score (partner→TUBB8P5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCSCN5A →+3.707+0.079.001<.00133
SKCMPLK4 →+5.208+0.036.001.00233
SKCMSVEP1 →+1.126+0.010.003<.00133
READOPCML →+3.302+0.035.006<.00133
UCECACTN4 →+1.230+0.174.009.00133
UCECZNF208 →+1.137+0.223.005<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,144 associations by consensus.

SCN5A by TUBB8P5 expression — HNSC

Box plot of SCN5A in TUBB8P5-low vs TUBB8P5-high samples in HNSC.

Explore this box plot interactively →

Exploration