TUBB7P

Across TCGA patient cohorts, TUBB7P mutation is significantly associated with the RNA expression of many other genes, with 1,163 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBB7P-associated genes across cancer lineages are EME1, WDHD1, and OR6Y1. Each is linked with TUBB7P in more than 2 cancer types. Because this analysis shows association rather than direction, both TUBB7P-to-partner and partner-to-TUBB7P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EME1 grouped by TUBB7P-low versus TUBB7P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB7P→partner) and Y-score (partner→TUBB7P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EME1 →	+0.843	+3.502	<.001	.002	3	3
UCEC	WDHD1 →	+0.854	+3.483	<.001	.002	3	3
HNSC	OR6Y1 →	+0.151	+5.368	<.001	.005	3	2
UCEC	PRSS53 →	+0.372	+3.254	<.001	.008	3	2
UCEC	ATP6V1C1 →	+0.503	+3.475	.009	.002	3	2
UCEC	DONSON →	+0.657	+3.467	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,163 associations by consensus.

EME1 by TUBB7P expression — UCEC

Explore this box plot interactively →