TUBB7P

Across TCGA patient cohorts, TUBB7P mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBB7P-associated genes across cancer lineages are EGFR_pY1068, NDRG1_pT346, and p62 Lck ligand. Each is linked with TUBB7P in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBB7P-to-partner and partner-to-TUBB7P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by TUBB7P-low versus TUBB7P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB7P→partner) and Y-score (partner→TUBB7P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.256	-2.321	.042	.035	3	1
UCEC	NDRG1_pT346 →	-0.525	-2.999	.033	.035	3	1
UCEC	p62 Lck ligand →	+0.503	+2.321	.002	.035	3	1
UCEC	Shc_pY317 →	-0.154	-3.459	.043	.005	3	1
UCEC	Tuberin →	+0.393	+2.321	.003	.035	3	1
UCEC	ATM →	-0.460	-3.459	.043	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

EGFR_pY1068 by TUBB7P expression — UCEC

Explore this box plot interactively →