TUBB4BP6

Across TCGA pan-cancer cohorts, TUBB4BP6 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated TUBB4BP6 data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher TUBB4BP6 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TUBB4BP6 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

ESCA, COAD, and READ are the cancer types where TUBB4BP6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	II,III,IV	0.908	0.416	.014	66	view →
COAD	OS	Tertile	IV	0.056	0.659	<.001	36	view →
READ	OS	Tertile	II,III,IV	0.187	0.644	.023	27	view →
GBM	OS	Tertile	All	0.220	0.416	.031	18	view →
BLCA	DFS	Tertile	III,IV	0.194	0.574	.023	18	view →
SKCM	DFS	Tertile	All	0.304	0.641	.033	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TUBB4BP6–ESCA (OS)

Open the ESCA breakdown →