TUBB4BP4

Across TCGA pan-cancer cohorts, TUBB4BP4 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated TUBB4BP4 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TUBB4BP4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TUBB4BP4 expression acts as an unfavorable survival marker, although some lineages such as LIHC show a favorable association.

HNSC, KIRC, and STAD are the cancer types where TUBB4BP4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	II,III,IV	0.129	0.722	<.001	90	view →
KIRC	DFS	Tertile	II,III,IV	0.062	0.762	<.001	54	view →
STAD	DFS	Tertile	III,IV	0.206	0.599	<.001	54	view →
COAD	OS	Tertile	All	0.185	0.799	.011	36	view →
THYM	DFS	Tertile	All	0.174	0.759	.028	27	view →
BLCA	DFS	Tertile	All	0.159	0.625	.016	27	view →
LIHC	DFS	Tertile	III,IV	1.000	0.169	.044	9	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

TUBB4BP4–HNSC (OS)

Open the HNSC breakdown →