Across TCGA cell cohorts, TUBB4B mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TUBB4B-associated genes across cancer lineages are NPHS2, MSGN1, and LCE1C. Each is linked with TUBB4B in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBB4B-to-partner and partner-to-TUBB4B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB4B→partner) and Y-score (partner→TUBB4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NPHS2 →	+0.073	+4.029	.009	.009	3	1
LARGE_INTESTINE	MSGN1 →	+0.100	+3.930	<.001	.003	3	1
LARGE_INTESTINE	LCE1C →	+0.062	+3.684	.004	.006	3	1
LARGE_INTESTINE	RNF212B →	+0.146	+3.678	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

TUBB4B survival (RNA) · tumor vs normal (RNA) · all TUBB4B data types