Across TCGA cell cohorts, TUBB4B mutation is significantly associated with the mutation status of many other genes, with 4,021 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TUBB4B-associated genes across cancer lineages are ADARB1, GPAA1, and UVRAG. Each is linked with TUBB4B in more than 2 cancer types. Because this analysis shows association rather than direction, both TUBB4B-to-partner and partner-to-TUBB4B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBB4B→partner) and Y-score (partner→TUBB4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ADARB1 →	+2.574	+4.182	.003	.003	1	3
LUNG_NSCLC_LUAD	GPAA1 →	+4.187	+5.000	.008	.008	1	3
LARGE_INTESTINE	UVRAG →	+2.574	+4.182	.003	.003	1	3
LUNG_NSCLC_LUAD	BAZ1A →	+4.772	+5.339	.004	.004	1	3
LARGE_INTESTINE	OR2W3 →	+3.744	+4.044	.003	.003	1	3
BLOOD_Leukemia	SPTBN4 →	+3.115	+4.080	.001	.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,021 associations by consensus.

Exploration

TUBB4B survival (RNA) · tumor vs normal (RNA) · all TUBB4B data types