TUBAP4

Across TCGA pan-cancer cohorts, TUBAP4 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated TUBAP4 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher TUBAP4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TUBAP4 expression acts as an unfavorable survival marker, although some lineages such as SKCM and LUAD show a favorable association.

MESO, SKCM, and DLBC are the cancer types where TUBAP4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	III,IV	0.321	0.608	<.001	117	view →
SKCM	OS	Tertile	III,IV	0.926	0.788	.008	42	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
COAD	DFS	Tertile	IV	0.251	0.547	.002	27	view →
READ	OS	Tertile	IV	0.289	0.899	<.001	24	view →
UVM	OS	Tertile	All	0.292	0.674	.035	18	view →
BLCA	DFS	Tertile	IV	0.148	0.486	.006	18	view →
UCEC	OS	Tertile	All	0.870	0.934	.014	18	view →
KIRC	DFS	Quartile	All	0.719	0.830	.003	13	view →
THYM	OS	Tertile	All	0.734	0.971	.020	6	view →
LUAD	OS	Tertile	All	0.591	0.328	.045	3	view →
ESCA	DFS	Tertile	All	0.272	0.394	.040	2	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

TUBAP4–MESO (OS)

Open the MESO breakdown →