Across TCGA pan-cancer cohorts, TUBAP14 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of TUBAP14’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TUBAP14 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TUBAP14 is over-expressed in tumor, although a few such as READ show the opposite, repressed pattern.
KIRC, HNSC, and KIRP are the cancer types where TUBAP14 tumor–normal differential expression is most reproducible.