TUBAL3

Across TCGA pan-cancer cohorts, TUBAL3 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TUBAL3 data layer compared with 22 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TUBAL3 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TUBAL3 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CCRCC show a favorable association.

HNSC, CCRCC, and LUAD are the cancer types where TUBAL3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	II,III,IV	0.774	0.450	.008	43	view →
CCRCC	OS	Quartile	All	1.000	0.718	.003	35	view →
LUAD	OS	Quartile	All	0.346	1.000	.012	13	view →
GBM	DFS	Median	All	0.506	0.283	.034	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TUBAL3–HNSC (DFS)

Open the HNSC breakdown →