TUBAL3

Across TCGA patient cohorts, TUBAL3 mutation is significantly associated with the RNA expression of many other genes, with 2,720 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBAL3-associated genes across cancer lineages are MIR1269B, RNA5SP414, and OR12D1. Each is linked with TUBAL3 in more than 2 cancer types. Because this analysis shows association rather than direction, both TUBAL3-to-partner and partner-to-TUBAL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR1269B grouped by TUBAL3-low versus TUBAL3-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBAL3→partner) and Y-score (partner→TUBAL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR1269B →	+0.733	+3.491	<.001	.008	3	3
UCEC	RNA5SP414 →	+0.531	+2.085	<.001	.001	3	3
READ	OR12D1 →	+0.108	+6.257	<.001	.001	3	2
LUAD	SNRPGP17 →	+0.436	+3.819	.001	.005	3	2
UCEC	RPS29P32 →	+0.375	+2.158	<.001	.001	3	2
COAD	RNA5SP86 →	+0.458	+4.335	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,720 associations by consensus.

MIR1269B by TUBAL3 expression — LUAD

Explore this box plot interactively →