TUBAL3

Across TCGA cell cohorts, TUBAL3 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TUBAL3-associated genes across cancer lineages are MYF5, GDF6, and HS3ST6. Each is linked with TUBAL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBAL3-to-partner and partner-to-TUBAL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYF5 grouped by TUBAL3-low versus TUBAL3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBAL3→partner) and Y-score (partner→TUBAL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MYF5 →	+0.006	+3.786	<.001	.002	3	1
BLOOD_Leukemia	GDF6 →	+0.651	+3.954	<.001	.001	3	1
BLOOD_Leukemia	HS3ST6 →	+0.011	+4.124	<.001	<.001	3	1
BLOOD_Leukemia	TLX3 →	+1.318	+3.266	.001	.003	3	1
BLOOD_Leukemia	KLK13 →	+0.284	+4.105	.009	.001	3	1
BLOOD_Leukemia	H1-8 →	+0.013	+3.507	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

MYF5 by TUBAL3 expression — BLOOD_Leukemia

Explore this box plot interactively →