Q-omics provides the consensus-scored TUBA5P profile across patient tissues and cancer cell-line models. TUBA5P expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, TUBA5P is differentially expressed in 17, with the highest sampling consensus in BLCA. Additionally, TUBA5P RNA expression shows 18,173 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight ACC, and BLCA as cancer lineages where TUBA5P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TUBA5P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TUBA5P survival associations across molecular data types. TUBA5P RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TUBA5P RNA expression–survival associations across cancer types. High TUBA5P expression shows unfavorable associations in ACC, MESO, SKCM and BRCA, but favorable associations in UVM and HNSC. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for TUBA5P RNA expression.
This table summarizes TUBA5P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 17. The strongest signals are observed in BLCA for RNA.
This table ranks reproducible tumor–normal expression differences for TUBA5P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TUBA5P shows lower tumor expression in KIRP and higher tumor expression in BLCA, LUAD, COAD, STAD and LIHC. The BLCA box plot shows higher TUBA5P RNA expression in tumor versus normal tissue (log2 FC = +2.391, t-test p < 0.001).
This table shows molecular features associated with TUBA5P in patient tissues and cancer cell lines. In patient samples, TUBA5P shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.
