TUBA4B

Across TCGA patient cohorts, TUBA4B protein abundance is significantly associated with the RNA expression of many other genes, with 1,080 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TUBA4B-associated genes across cancer lineages are LGALS1, CYP2D6, and HMOX1. Each is linked with TUBA4B in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBA4B-to-partner and partner-to-TUBA4B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TUBA4B versus LGALS1 in GBM, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBA4B→partner) and Y-score (partner→TUBA4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LGALS1 →	+1.212	+1.458	<.001	<.001	3	1
GBM	CYP2D6 →	-0.694	-0.977	<.001	.006	3	1
GBM	HMOX1 →	+2.023	+1.744	<.001	<.001	3	1
GBM	MYH9 →	+0.775	+1.117	.002	.004	3	1
GBM	NIN →	-0.431	-1.030	.005	.009	3	1
GBM	PYGL →	+0.877	+1.141	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,080 associations by consensus.

TUBA4B vs LGALS1 — GBM

Explore this scatter interactively →