TUBA4B

Across TCGA cell cohorts, TUBA4B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,282 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TUBA4B-associated GO terms across cancer lineages are Somatic diversification of immunoglobulins, Immunoglobulin production, and Production of molecular mediator of immune response. Each is linked with TUBA4B in more than 5 cancer types. Because this analysis shows association rather than direction, both TUBA4B-to-partner and partner-to-TUBA4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Somatic diversification of immunoglobulins grouped by TUBA4B-low versus TUBA4B-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBA4B→partner) and Y-score (partner→TUBA4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Somatic diversification of immunoglobulins →	+0.056	+0.231	<.001	<.001	3	6
BLOOD_Lymphoma	Immunoglobulin production →	+0.053	+0.205	<.001	<.001	3	6
BLOOD_Lymphoma	Production of molecular mediator of immune response →	+0.052	+0.205	<.001	<.001	3	6
BONE	Regulation of protein localization to nucleus →	+0.054	+0.061	.001	.009	3	6
LUNG_SCLC	Ribonucleotide metabolic process →	+0.047	+0.368	.001	.005	3	6
PANCREAS	Protein catabolic process at synapse →	+0.083	+0.078	<.001	.009	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,282 associations by consensus.

Somatic diversification of immunoglobulins by TUBA4B expression — BLOOD_Lymphoma

Explore this box plot interactively →