Across TCGA patient cohorts, TUBA3C mutation is significantly associated with the RNA expression of many other genes, with 4,024 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBA3C-associated genes across cancer lineages are PIEZO1P2, NCAPD3, and BAG3. Each is linked with TUBA3C in more than 2 cancer types. Because this analysis shows association rather than direction, both TUBA3C-to-partner and partner-to-TUBA3C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBA3C→partner) and Y-score (partner→TUBA3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	PIEZO1P2 →	+0.023	+4.816	<.001	.003	3	3
UCEC	NCAPD3 →	+0.507	+1.903	.001	<.001	3	3
UCEC	BAG3 →	+0.615	+2.485	<.001	<.001	3	3
UCEC	ENTR1 →	+0.409	+2.431	<.001	.001	3	3
COAD	CXCL10 →	+1.605	+2.598	.001	.006	3	3
UCEC	SLC7A4 →	-0.846	-1.860	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,024 associations by consensus.

Exploration

TUBA3C survival (RNA) · tumor vs normal (RNA) · all TUBA3C data types