Across TCGA patient cohorts, TUBA3C mutation is significantly associated with the total protein of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBA3C-associated genes across cancer lineages are EGFR_pY1068, PCNA, and ASNS. Each is linked with TUBA3C in more than 2 cancer types. Because this analysis shows association rather than direction, both TUBA3C-to-partner and partner-to-TUBA3C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBA3C→partner) and Y-score (partner→TUBA3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	EGFR_pY1068 →	-0.421	-3.700	.048	.001	3	3
COAD	PCNA →	+0.322	+2.593	.001	.006	3	3
LUAD	ASNS →	+0.858	+3.321	<.001	.009	3	3
UCEC	MEK1 →	+0.420	+3.169	<.001	<.001	3	3
LUAD	GSK3-a-b →	+0.258	+3.321	<.001	.009	3	2
LUAD	c-Jun_pS73 →	-0.181	-2.974	.011	.035	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

Exploration

TUBA3C survival (RNA) · tumor vs normal (RNA) · all TUBA3C data types