Across TCGA cell cohorts, TUBA3C mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TUBA3C-associated genes across cancer lineages are IQCF6, SKOR2, and MT1HL1. Each is linked with TUBA3C in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBA3C-to-partner and partner-to-TUBA3C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBA3C→partner) and Y-score (partner→TUBA3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	IQCF6 →	+0.247	+3.882	<.001	.001	3	1
LARGE_INTESTINE	SKOR2 →	+0.003	+4.022	<.001	.006	3	1
LARGE_INTESTINE	MT1HL1 →	+0.058	+4.022	<.001	.006	3	1
BLOOD_Lymphoma	KRT71 →	+0.013	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	REG3G →	+0.044	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	IFNL3 →	+0.142	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

TUBA3C survival (RNA) · tumor vs normal (RNA) · all TUBA3C data types