TUBA1B

Across TCGA cell cohorts, TUBA1B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,908 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TUBA1B-associated GO terms across cancer lineages are Positive regulation of mitotic cytokinesis, Positive regulation of chromosome separation, and Regulation of mitotic metaphase/anaphase transition. Each is linked with TUBA1B in more than 18 cancer types. Because this analysis shows association rather than direction, both TUBA1B-to-partner and partner-to-TUBA1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitotic cytokinesis grouped by TUBA1B-low versus TUBA1B-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBA1B→partner) and Y-score (partner→TUBA1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of mitotic cytokinesis →	+0.145	+1.478	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Positive regulation of chromosome separation →	+0.211	+1.819	<.001	<.001	3	19
STOMACH	Regulation of mitotic metaphase/anaphase transition →	+0.111	+1.237	<.001	.001	3	19
SOFT_TISSUE	Regulation of sister chromatid segregation →	+0.098	+0.672	<.001	<.001	3	19
PANCREAS	Positive regulation of cytokinesis →	+0.148	+1.031	<.001	<.001	3	19
BLOOD_Myeloma	Regulation of chromosome segregation →	+0.135	+1.593	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,908 associations by consensus.

Positive regulation of mitotic cytokinesis by TUBA1B expression — URINARY_TRACT

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