TUBA1A

Across TCGA patient cohorts, TUBA1A mutation is significantly associated with the RNA expression of many other genes, with 545 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TUBA1A-associated genes across cancer lineages are CIDECP1, IGHD6-6, and RN7SL332P. Each is linked with TUBA1A in more than 1 cancer types. Because this analysis shows association rather than direction, both TUBA1A-to-partner and partner-to-TUBA1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CIDECP1 grouped by TUBA1A-low versus TUBA1A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBA1A→partner) and Y-score (partner→TUBA1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CIDECP1 →	+0.323	+1.960	.002	.009	3	2
UCEC	IGHD6-6 →	+0.688	+2.513	<.001	.007	3	2
UCEC	RN7SL332P →	+0.114	+3.038	<.001	.006	3	2
LUAD	DPPA2 →	+0.934	+4.293	.009	.008	3	2
UCEC	AIM2 →	+0.870	+2.617	<.001	.005	3	2
UCEC	MOCS2 →	+0.441	+3.507	.003	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 545 associations by consensus.

CIDECP1 by TUBA1A expression — UCEC

Explore this box plot interactively →