TUBA1A

Across TCGA cell cohorts, TUBA1A mutation is significantly associated with the RNA expression of many other genes, with 404 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible TUBA1A-associated genes across cancer lineages are CFD, CSGALNACT2, and PLA2G3. Each is linked with TUBA1A in more than 3 cancer types. Because this analysis shows association rather than direction, both TUBA1A-to-partner and partner-to-TUBA1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFD grouped by TUBA1A-low versus TUBA1A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TUBA1A→partner) and Y-score (partner→TUBA1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CFD →	+1.195	+3.321	.002	.003	3	3
PANCREAS	CSGALNACT2 →	-0.810	-3.169	.003	.006	3	2
STOMACH	PLA2G3 →	+1.149	+3.240	.004	.003	3	2
LUNG_NSCLC_LUAD	GDPD3 →	+1.679	+3.358	.001	.003	3	2
LUNG_NSCLC_LUAD	TBCB →	-0.640	-3.139	.005	.008	3	2
LUNG_NSCLC_LUAD	FAM83A →	+2.425	+3.358	.002	.003	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 404 associations by consensus.

CFD by TUBA1A expression — LARGE_INTESTINE

Explore this box plot interactively →