TTYH3

Across TCGA cell cohorts, TTYH3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,714 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TTYH3-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Cell division, and Positive regulation of leukocyte differentiation. Each is linked with TTYH3 in more than 12 cancer types. Because this analysis shows association rather than direction, both TTYH3-to-partner and partner-to-TTYH3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by TTYH3-low versus TTYH3-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TTYH3→partner) and Y-score (partner→TTYH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of calcium ion export across plasma membrane →	+0.078	+1.168	.001	<.001	3	13
BREAST	Cell division →	+0.114	+2.128	<.001	<.001	3	13
LIVER	Positive regulation of leukocyte differentiation →	+0.072	+1.343	.002	.003	3	12
LIVER	Positive regulation of hemopoiesis →	+0.072	+1.343	.002	.003	3	12
STOMACH	Regulation of cell morphogenesis →	+0.048	+1.575	.001	<.001	3	12
BREAST	Endocytic recycling →	+0.073	+1.468	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,714 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by TTYH3 expression — OESOPHAGUS

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