TTYH2

Across TCGA patient cohorts, TTYH2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,808 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TTYH2-associated genes across cancer lineages are ISM2, CCL7, and OR6F1. Each is linked with TTYH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TTYH2-to-partner and partner-to-TTYH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTYH2 versus ISM2 in LSCC, with a Pearson correlation of -0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTYH2→partner) and Y-score (partner→TTYH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ISM2 →	-0.799	-1.551	.007	.002	3	2
LSCC	CCL7 →	-1.334	-1.695	.001	.001	3	2
GBM	OR6F1 →	+0.071	+0.476	.006	.002	3	2
GBM	CACNB4 →	+0.642	+0.564	<.001	.005	3	2
LSCC	RNASE10 →	-0.727	-1.567	.009	<.001	3	2
LSCC	RACK1 →	-0.386	-1.811	.004	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,808 associations by consensus.

TTYH2 vs ISM2 — LSCC

Explore this scatter interactively →